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In model plant Arabidopsis there are myosin
2025-01-20

In model plant Arabidopsis, there are 13 myosin XI isoforms (XI-1, XI-2, XI-A, XI-B, XI-C, XI-D, XI-E, XI-F, XI-G, XI-H, XI-I, XI-J, and XI-K) and 4 myosin VIII isoforms (ATM1, ATM2, VIII-A, VIII-B) [9,13]. Arabidopsis myosin XIs have the common domain composition: a motor domain that interacts with
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The geometry of two three
2025-01-18

The geometry of two, three, four and five Dasatinib Monohydrate sale neutral radical ACh molecule complexes with various electronic configurations, i.e. with various multiplicities equal to 1, 2 and 4 (for ACh trimer) were determined using DFT with the unrestricted B97d/SVP potential/basis set in G
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A previous study reported that the
2025-01-18

A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial
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Defining the multiple roles of autophagy in
2025-01-18

Defining the multiple roles of autophagy in stroke has been a rapidly evolving and exciting venue for translational research, with innovative products being applied from bench to bedside. Spanning pharmacological pathway manipulation and functional experimental validation, altered autophagy activati
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W 54011 br Autophagy in the central nervous
2025-01-18

Autophagy in the central nervous system The autophagic process appears to be very important for the cells of the central nervous system, as it allows to maintain the functional integrity of the nervous tissue. Indeed macroautophagy is involved in the regulation of homeostasis of the CNS, playing
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br Acknowledgement This work was funded by
2025-01-18

Acknowledgement This work was funded by NIH/NINDS grant number NS080967 to C. Waites. Introduction Macro-autophagy also called autophagy is a conserved pathway for the lysosomal degradation and recycling of intracellular materials. It is instrumental for the homeostasis of cells and tissues a
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br Materials and methods br Results
2025-01-18

Materials and methods Results Dried Benzoylmesaconitine used were 48.46 g C. benghalensis, 857.98 g T. zebrina and 25.09 g T. fluminensis. The samples gave 12.9% C. benghalensis, 0.078% T. zebrina and 3.06% T. fluminensis methanol extracts. The methanol extracts were evaluated for their lipox
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The tumor suppressor function of LOX in normal
2025-01-18

The tumor-suppressor function of 15-LOX-2 in normal prostate epithelial cells may be explained by the induction of replicative senescence [14,15]. Thus, 15-LOX-2 is overexpressed in age-dependent prostatic hyperplasia, but cell senescence may hinder progression to malignant transformation. Notwithst
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IL-1β suppression Coincident with APJ receptor several cell
2025-01-18

Coincident with APJ receptor, several cell types in the body can synthesize apelin protein. For example, the highest apelin concentrations in the body have been found in the rat central nervous system, pituitary gland, lungs, cardiac muscle, gastrointestinal tract and mammary glands, with lower valu
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The transcription factor activator protein AP is a redox
2025-01-18

The transcription factor activator protein-1 (AP-1) is a redox-sensitive transcription factor whose activity is controlled by agents that perturb intracellular thiol concentrations [10,11]. AP-1 is mainly composed of Jun, Fos, and ATF protein dimers [12,13]. AP-1 mediates the regulation of numerous
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Besides above mentioned UV visible and fluorescence spectros
2025-01-18

Besides above-mentioned UV–visible and fluorescence spectroscopy methods, electron paramagnetic resonance (EPR) spectroscopy, the only analytical method that detect compounds having unpaired electrons known as free radicals, was rarely used in antioxidant capacity measurement (Amarowicz et al., 2004
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br Conclusions br Acknowledgments br Introduction The surfac
2025-01-18

Conclusions Acknowledgments Introduction The surface water bodies are affected by effluents containing pollutants from wastewater treatment plants, storm water overflows and run-off from non-point sources like agricultural land and urban city surfaces. This relates to land-based sources occ
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br Eprosartan The AT R antagonist eprosartan is
2025-01-18

Eprosartan The AT1R antagonist eprosartan is approved for the treatment of essential Ac-Endothelin-1 (16-21), human and may be administered using a convenient once-daily regimen. The drug is a well-tolerated and effective antihypertensive agent with benefit in the secondary prevention of cerebro
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br Materials and methods br Results br
2025-01-18

Materials and methods Results Discussion Prostate cancer is the most common cancer in men in the United States and the second leading cause of cancer death. Therapeutic interventions include mainly: radical prostatectomy or radiation therapy (RT), with or without androgen deprivation therap
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Various compounds have been designed to
2025-01-17

Various compounds have been designed to inhibit aldose reductase (AR) [12]. These compounds can be classified into two main categories, the first category comprises those containing a carboxylic Caspase-4 Colorimetric Assay Kit synthesis moiety, for example, 3-thiazolidineacetic acid derivative, wh
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