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br Method of literature search br Disclosures br Acknowledgm
2023-06-27

Method of literature search Disclosures Acknowledgment The authors thank and acknowledge Mrs. Jaini Parekh, BFA, for illustrating the diagram in Figure 1. An overview of angiogenesis Angiogenesis is a biological process through which there is the formation of new blood vessels from pre-
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Therefore a number of homoisoflavonoids
2023-06-27

Therefore, a number of homoisoflavonoids may be designed in future that may be effective against angiogenesis for treating ocular neovascularization. As this Bleomycin Sulfate current study deals with robust molecular modeling techniques on SH-11037 (cpd 15) and related homoisoflavonoids and SH-1103
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Accumulating evidence suggest that patients with advanced po
2023-06-20

Accumulating evidence suggest that patients with advanced -positive NSCLC are at increased risk of VTE or coagulation disorders during the course of their disease, indicating that cancer genotype might play a role in the occurrence of cancer-related thromboembolism . Here we report the case of a pat
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br Conflict of interest br Acknowledgement This study was
2023-06-17

Conflict of interest Acknowledgement This study was supported by a grant from University Grants Commission - Basic Scientific Research (UGC-BSR), New Delhi, India (UGC-BSR No:F-7-115/2007). Introduction The G protein-coupled receptors activated by extracellular adenosine (Ado), called Aden
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encorafenib br Introduction br Rac dependent ROS and
2023-06-16

Introduction Rac1-dependent ROS and encorafenib regulation in neuronal functions NOX-mediated ROS have an important role as physiological messengers. One remarkable example regarding such a function is during axonal formation. In this line, increased p40phox/NOX2 levels and co-localization at
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Accumulating data suggest that ROS trigger
2023-06-13

Accumulating data suggest that ROS trigger autophagy but, in turn, autophagy reduces ROS levels [23]. Our results are in agreement because 27-OH mediated autophagy induction interms of LC3 II formation and Beclin 1 protein expression was suppressed by treating the promonocytic cells with the antioxi
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br Acknowledgements br Introduction Thus damage to the nervo
2023-06-13

Acknowledgements Introduction Thus, damage to the Sunitinib may produce severe consequences (National Research Council, 1992). Indeed, though the nervous system has several compensatory and adaptive mechanisms, it is vulnerable to toxic insult, due to its inability to regenerate after lethal
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The original Aurora kinase was identified during
2023-06-13

The original Aurora kinase was identified during a phenotypic screen for defects in mitotic spindles in Drosophila mutants. Aurora mutants were so named because of the morphological defects at the mitotic spindle resembling the Aurora borealis, or the Northern light [4]. The structure of the Auroras
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br Experimental section br Acknowledgments br Introduction
2023-06-12

Experimental section Acknowledgments Introduction Adipose is a major endocrine organ which releases a range of bioactive agents [1]. Selected adipose depots have been established as sites of sex steroid metabolism [1]. Subcutaneous and visceral adipose express high levels of aromatase, cap
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br Experimental section br Acknowledgments br Introduction
2023-06-12

Experimental section Acknowledgments Introduction Adipose is a major endocrine organ which releases a range of bioactive agents [1]. Selected adipose depots have been established as sites of sex steroid metabolism [1]. Subcutaneous and visceral adipose express high levels of aromatase, cap
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Hepatic inflammation and fibrosis are hallmarks of the NASH
2023-06-06

Hepatic WP1130 and fibrosis are hallmarks of the NASH phenotype and are thought to occur in a subset of patients with NAFLD. While it is hypothesized that therapeutic lowering of hepatic lipids will be sufficient to improve hepatic fibrosis and inflammation secondarily, this remains controversial a
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br Material and methods br Results br Discussion In
2023-06-06

Material and methods Results Discussion In order to find new and improved ways of treating type 2 diabetes (T2D) and other related conditions it is vital that investigators gain a more in-depth understanding of the effects that anti-diabetic treatments, such as TZDs, have on molecules impli
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MD was the recipient of
2023-06-03

MD was the recipient of the Intergroupe Francophone de Cancérologie Thoracique (IFCT) Alain Depierre Grant in 2014. JP was the recipient of the ARISTOT (Association de Recherche, d’Information Scientifique et Thérapeutique en Oncologie Thoracique) grant in 2016. Conflicts of interest statement
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Extracellular adenosine acts as a local modulator of
2023-06-01

Extracellular adenosine acts as a local modulator of cell function via four adenosine receptor subtypes (A1Rs A2AR, A2BR, and A3R) that are involved in numerous physiological and pathophysiological processes [31]. Each is encoded by a separate gene and has different functions, although with some ove
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Our study like that of Zill et al included European
2023-05-30

Our study, like that of Zill et al. (2012) included European Caucasians, although their population was much smaller (n=162) and more heterogeneous (19–72years). Further, potential confounding or effect modification by other health, lifestyle or genetic factors was not considered. These differences m
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